(Received: July 8, 2004; Accepted for publication: September 6, 2004; Published on Web: November 19, 2004)
The program which calculates topological resonance energy was transplanted from BASIC computer to Windows computer. Part of the program was revised to be able to handle data input and output with a worksheet of Excel. With the transplanted program, the topological resonance energy of PCDD was calculated. Relationships between topological resonance energy and some biological activity were examined. It was suggested that the topological resonance energy could be used when acute toxicity of PCDD was predicted.
Keywords: Topological resonance energy, Excel/VBA, Dioxin, LD50-30, Enzyme induction activity, TEF
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