$BeN.!&CfN.!&2 $BEl5~B?K`@n$N?e

$B?@It(B $B=g;R(B, $BJ!ED(B $BJ~;R(B, $BD9Eh(B $B1@J<(B, $B@D;3(B $BCRIW(B


Return

1 $B$O$8$a$K(B

$B6aG/!"MM!9$J4D6-J]A4LdBj$,CmL\$5$l$F$$$k!#FC$K2O@n$N?eeN.!"CfN.$*$h$S2eN.!&CfN.!&21]$B$H$7$F$b$C$H$b9-$/MQ$$$i$l$F$$$k2=3XE*B?JQNLE}7W2r@O$N0l$D$G$"$k2, 3]$B$r9T$$!"%Q%i%a!<%?$N5sF0$r2r@O$7$?!#JPHyJ,78?t2r@O$O!"%K%e!<%i%k%M%C%H%o!<%/$K$h$kJ,N`$KBP$9$kF~NOJQ?t$N46 $BK\8&5f$G9T$C$?El5~ET$NB?K`@n$N?ee$G:NeN.!"CfN.$*$h$S2eN.$HCfN.!&2eN.$+$iCfN.0h$N?e $BK\Js9p$G$O!"@~7A2r@OeN.!&CfN.!&2 $BHs@~7A2r@O

2 $B2r@O%G!<%?(B

$B2r@O$KMQ$$$?2O@n$N?e4]$B$N$&$A$+$i!"8;N.$+$i2O8}$^$G$N%G!<%?$,Hf3SE*6Ql=j$H%5%s%W%k$NJ,@O5!4X$r(BTable 1$B$K<($9!#$^$?!"(B17$B$N%5%s%W%k:NFigure 1$B$K<($9!#(B

Table 1. Sampling Points and Agency of Analysis

Sampling PointsAgency
1$BOBED66(B$BEl5~ET(B
2$BD4I[66(B$B7z@_>J(B
3$B1)B<1a(B$BEl5~ET(B
4$B1JED66(B$B7z@_>J(B
5$BGREg86?eJd5kE@(B$BEl5~ET(B
6$BGREg66(B$B7z@_>J(B
7$BF|Ln66(B$B7z@_>J(B
8$B4X8M66(B$B7z@_>J(B
9$B@'@/66(B$B7z@_>J(B

Sampling PointsAgency
10$BB?K`@n8666(B$B7z@_>J(B
11$BB?K`?eF;66(B$B7z@_>J(B
12$B5N2<$BEl5~ET(B
13$BBh;05~IMB?K`@n66(B$B7z@_>J(B
14$BD4I[$BEl5~ET(B
15$BED1`D4I[1a>e(B$B7z@_>J(B
16$BO;6?66(B$B7z@_>J(B
17$BBg;U66(B$B7z@_>J(B
 


Figure 1. Schematic Map of Sampling Points along Tamagawa River, Tokyo, JAPAN

$B!V8x6&MQ?e0h$*$h$SCO2eN.0h!"B,DjE@#7$NF|Ln66$+$iB,DjE@(B15$B$NED1`D4I[1a$^$G$rCfN.0h!"B,DjE@(B16$B$H(B17$B$NO;6?66$HBg;U66$r2eN.!"CfN.!"2 $B!V8x6&MQ?e0h$*$h$SCO2e#87n$N%G!<%?$rMQ$$$?2r@O7k2L$N5-=R$O3d0&$9$k!#!K(B
Table 2$B$K%Q%i%a!<%?$N@bL@$HN,9f!"(BTable 3$B$K2r@O$KMQ$$$?%G!<%?$r<($7$?!#(BTable 2$B$*$h$S(BTable 3$B$K$O!">eN.!"CfN.!"2

Table 2. Abbreviations and explanation of chemical index of water analysis
$BB,Dj9`L\(B$BN,>N(B$BHw9M(B
$B>eN.!&CfN.!&2pos$B>eN.(B:1$B!"CfN.(B:2$B!"2
$B?eAG%$%*%sG;EY(BpH$B3$?e$d@P3%4d$N1F6A$rl9g$,$"$k!#(B
$BMOB8;@AGNL(BDO$BNL$,>/$J$$J}$,2O@n$O1x@w$5$l$F$$$k!#(B
$B@8J*2=3XE*;@AGMW5aNL(BBOD$B9%5$@-Hy@8J*$NM-5!M\J,J,2r$N:]$K>CHq$9$k;@AG>CHqNL!#(B
$B2=3XE*;@AGMW5aNL(BCOD$B;@AG$r>CHq$9$kJ*
$BA4CbAG(BT-N$B@8J*$N@80i$K$H$C$F7g$/$3$H$N$G$-$J$$1IM\1vJ,!#(B
$BA4%j%s(BT-P$B@8J*$N@80i$K$H$C$F7g$/$3$H$N$G$-$J$$1IM\1vJ,!#(B
$B1v2=J*%$%*%s(BCl-$B3$?e$N1F6A$ru67$N;XI8!#(B
$B%"%s%b%K%"@-CbAG(BNH4-N$B$7G"$K$h$k1x@w$K$O%"%s%b%K%&%`%$%*%s$,8!=P$5$l$k!#(B
$B0!>K;@@-CbAG(BNO2-N$B>K;@%$%*%s$N4T85$"$k$$$O%"%s%b%K%"$N;@2=$K$h$C$F@8$:$k!#(B
$B>K;@@-CbAG(BNO3-N$B0lHL$NC8?e$K$O(B0.1$B!A#1(Bmg$B!?(Bl$B0J>e4^$^$l$k!#(B
$B%j%s;@@-%j%s(BPO4-P$B@83hGS?e$N1F6A$r
$BEE5$EAF3N((BCOND$B@6@!$J2O@n$G$ODc$/!"1xBy$N?J$s$@>l9g5U$K9b$$CM$r<($9!#(B

$B5]$B$rMQ$$!"%K%e!<%i%k%M%C%H%o!<%/$K$O!"2f!9$,3+H/$7$F$$$kJ,;R$N9=B$3h@-Aj4X2r@O$N$?$a$N%K%e!<%i%k%M%C%H%o!<%/%7%_%e%l!<%?(B: Neco (NEural network simulator for structure-activity COrrelation of molecules)[6 - 11]$B$rMQ$$$?!#F~NOJQ?t$NJPHyJ,7W;;$O?7$?$K

Table 3. Values of chemical index of water analysis (1997-1999)
1997 Feb.pos.pHDOBODCODT-NT-PCl-NH4-NNO2-NNO3-NPO4-PCOND
$B-!OBED66(B17.612.30.51.20.770.00820.010.0020.720.003108
$B-"D4I[66(B17.712.40.511.020.01120.010.0020.960.005106
$B-#1)B<1a(B17.813.50.51.40.930.01430.010.0020.830.010118
$B-$1JED66(B18.012.10.51.61.350.01140.020.0051.200.007134
$B-%GREg86?eJd5kE@(B18.615.50.51.22.240.00860.010.0072.030.003179
$B-&GREg66(B18.212.81.11.62.670.01170.020.0082.530.009155
$B-'F|Ln66(B27.810.52.04.77.190.557280.520.1786.010.506284
$B-(4X8M66(B27.710.42.85.16.640.496280.800.2275.210.462296
$B-)@'@/66(B27.811.01.84.96.130.596300.590.2054.950.572316
$B-*B?K`@n8666(B27.18.85.08.19.240.763410.670.5897.470.635341
$B-+B?K`?eF;66(B27.410.64.37.28.340.663370.720.4076.470.546318
$B-,5N2<27.711.93.35.68.580.633350.020.3506.560.571376
$B--Bh;05~IMB?K`@n66(B27.410.74.26.57.680.603360.530.3676.530.500317
$B-.D4I[27.711.22.75.67.480.540360.050.2616.620.479378
$B-/ED1`D4I[1a>e(B27.511.13.66.47.640.610380.510.3436.230.481315
$B-0O;6?66(B37.49.62.06.38.130.51434002.160.3534.790.4258670
$B-1Bg;U66(B37.59.32.15.26.420.37282201.120.2813.380.30218100

1998. Feb.pos.pHDOBODCODT-NT-PCl-NH4-NNO2-NNO3-NPO4-PCOND
$B-!OBED66(B17.311.90.50.90.680.00810.010.0020.620.00597
$B-"D4I[66(B18.012.10.51.30.610.01920.050.050.570.005101
$B-#1)B<1a(B17.212.60.50.90.650.01220.010.0020.590.006104
$B-$1JED66(B18.112.30.61.70.750.02620.050.050.590.006125
$B-%GREg86?eJd5kE@(B17.312.70.50.91.370.01250.010.0041.050.007135
$B-&GREg66(B18.012.20.71.71.100.02930.050.050.880.011148
$B-'F|Ln66(B27.59.72.86.57.640.894430.960.266.020.801391
$B-(4X8M66(B27.38.92.75.58.340.598370.790.196.790.508379
$B-)@'@/66(B27.69.72.06.38.910.756410.590.197.680.669427
$B-*B?K`@n8666(B27.39.83.17.39.800.891500.430.288.740.780379
$B-+B?K`?eF;66(B27.410.03.86.59.550.856440.450.348.030.764348
$B-,5N2<27.510.61.75.19.080.636390.150.1618.240.581384
$B--Bh;05~IMB?K`@n66(B27.510.52.86.29.130.687430.590.267.920.618355
$B-.D4I[27.29.36.86.28.180.665390.650.1676.170.353392
$B-/ED1`D4I[1a>e(B27.610.92.66.18.960.710430.480.247.850.648353
$B-0O;6?66(B37.69.6118.98.540.741112000.480.163.290.14327400
$B-1Bg;U66(B37.910.04.75.35.860.314130000.410.153.110.25831400

1999. Feb.pos.pHDOBODCODT-NT-PCl-NH4-NNO2-NNO3-NPO4-PCOND
$B-!OBED66(B17.412.30.51.00.620.00810.010.0020.560.00395
$B-"D4I[66(B17.812.80.51.30.620.01120.050.0050.550.008106
$B-#1)B<1a(B17.312.90.51.10.610.02420.010.0020.490.003104
$B-$1JED66(B17.912.90.51.50.650.01220.050.0050.560.008116
$B-%GREg86?eJd5kE@(B17.213.90.61.11.060.01030.010.0030.940.005131
$B-&GREg66(B17.912.70.51.41.110.02230.050.0051.020.010148
$B-'F|Ln66(B27.510.13.16.36.950.816360.830.2765.440.72382
$B-(4X8M66(B27.510.84.26.97.790.713350.990.3486.090.634397
$B-)@'@/66(B27.510.72.47.08.060.770390.570.2606.680.707413
$B-*B?K`@n8666(B27.310.13.57.09.150.829410.420.3277.850.708464
$B-+B?K`?eF;66(B27.510.72.46.39.430.837410.430.2947.620.731448
$B-,5N2<27.310.91.45.18.930.677390.170.1808.200.659380
$B--Bh;05~IMB?K`@n66(B27.511.22.05.58.910.685400.410.2077.700.568445
$B-.D4I[27.49.71.55.09.230.663360.280.1837.780.634386
$B-/ED1`D4I[1a>e(B27.711.51.75.58.790.733400.260.2047.310.641454
$B-0O;6?66(B37.49.82.66.38.710.48442103.040.2424.480.38814600
$B-1Bg;U66(B37.69.02.34.84.740.270102030.720.1842.410.21834100

3 $B $BK\@a$G$O!"@h$K@bL@$7$?2O@n$N?eeN.!&CfN.!&2 $B>eN.!"CfN.!"2 Figure 2 $B$H(BFigure 3$B$K#3G/J,$N%G!<%?$KBP$9$kBh0l4-N$B!&(BNO3-N$B!&(BNO2-N$B!&(BPO4-P$B$N#8%Q%i%a!<%?$,@5$NBg$-$J4sM?$r$7$F$*$j!"(BpH$B$H(BDO$B$OBg$-$/Ii$N4sM?$r$7$F$$$k!#Bh0l-$B$H(BCOND$B$N4sM?$OB>$N%Q%i%a!<%?$KHf$Y>.$5$$!#(B


Figure 2. Sorted coefficients in the first principal component


Figure 3. Sorted coefficients in the second principal component

$B5U$KBhFs-$B$H(BCOND$B$N%Q%i%a!<%?$,Bg$-$J4sM?$r$7$F$*$j!"B>$N%Q%i%a!<%?$N4sM?$O>.$5$$!#$D$^$j!"BhFs-$B$H(BCOND$B$N4sM?$rBeI=$7$F$$$k$H$$$&$3$H$,$G$-$k!#(BBOD$B!"$d(BNH4-N$B$*$h$S(B PO4-P$B$^$?(BNO3-N$B$b4sM?$9$k$,!"$=$l$i$N1F6A$O(BCl-$B$H(BCOND$B$h$j>.$5$$!#(B
$BBh0lTable 4$B$K<($7$?!#$^$?(BFigure 4$B$K$O!"$3$NF@E@$rMQ$$$?(BK-L$B%W%m%C%H$r<($7$?!#(BTable 4$B$*$h$S(BFigure 4$B$r$_$k$H!">eN.0h!J#1$+$i#6!K!"CfN.0h!J#7$+$i(B15$B!K!"2eN.$HCfN.!&2J}BhFseN.!&CfN.$H2

Table 4. REGR factor score of the first and second principal components
199719981999
PositionposFirstSecondFirstSecondFirstSecond
11-3.416-0.059-3.2-0.102-3.35-0.106
21-3.475-0.069-3.50.0834-3.65-0.027
31-3.742-0.142-3.29-0.205-3.4-0.198
41-3.4340.0385-3.510.1037-3.7-0.006
51-4.469-0.229-3.25-0.234-3.46-0.36
61-3.34-0.035-3.330.0643-3.55-0.034
720.6631-0.5872.547-0.72.139-0.615
820.8876-0.2961.956-0.4712.411-0.486
920.5345-0.6072.042-0.8692.058-0.926
1024.2193-0.6623.152-1.1572.886-1.005
1122.5541-0.5623.009-1.0142.326-1.143
1221.3003-0.9921.282-1.1281.468-1.326
1322.0611-0.5782.104-0.8831.423-1.038
1420.8614-0.8162.3030.0651.665-1.07
1521.6896-0.6251.849-0.9741.197-1.138
1632.42561.43072.9745.43142.582.532
1731.26563.18770.6755.48270.5585.0519

$B$h$j>\:Y$K$_$k$HBhFse$NNN0h$,2eN.0h!"Bh0leN.!&CfN.!&2-$B$H(BCOND$B$,>eN.!&CfN.!&2eN.!&CfN.!&2Figure 4$B$G$O!"(B1997$BG/$KHf$Y(B1998$BG/$O1x@w$,?J$_!"(B1999$BG/$K$o$:$+$K1x@w$NEY9g$$$,2~NI$5$l$?$3$H$r;G$&$3$H$,$G$-$k!#FC$K2


Figure 4. the K-L plot of component score

$B$3$l$i$N7k2L$r?eeN.$HCfN.!&2eN.0h$+$iCfN.0h$N?e.$5$$$H$$$&$3$H$,$$$($k!#8@$$49$($k$H>eN.$+$iCfN.$X0\$kCJ3,!JCOE@(B6$B$H(B7$B$N4V!K$GN.F~$9$k;YN.$N1x@w$r=|5n$9$kEy!"CfN.0h$G$N?e/$J$/$9$k$3$H$,B?K`@n$N4D6-J]A4$r9T$&>e$G=EMW$G$"$k$3$H$,<(:6$5$l$?!#(B

4 $B#3AX%Q!<%;%W%H%m%s7?%K%e!<%i%k%M%C%H%o!<%/$NF~NO%Q%i%a!<%?$NJPHyJ,78?t2r@O$N7k2L(B

$B@D;3$N3+H/$7$?#3AX%Q!<%;%W%H%m%s7?%K%e!<%i%k%M%C%H%o!<%/$NF~NO%Q%i%a!<%?$NJPHyJ,78?t2r@OK!(B[2, 3]$B$r?7$?$K2f!9$,3+H/Cf$N%Q!<%;%W%H%m%s7?%K%e!<%i%k%M%C%H%o!<%/%7%_%e%l!<%?(BNeco[6 - 11]$B$K $BK\8&5f$GMQ$$$?;0AX%Q!<%;%W%H%m%s7?%M%C%H%o!<%/$O!"F~NOAX!"Cf4VAX!"=PNOAX%K%e!<%m%s?t$,$=$l$>$l(B13,12,3$B$G$"$k!#F~NOAX$K$O(B12$Bo$K(B1.0$B$NCM$N%P%$%"%9$rF~NO$7!"=PNOAX$O>eN.!"CfN.!"2$l!"I=8=$9$k$b$N$H$7$?!#Cf4VAX%K%e!<%m%s?t$O!"#3G/J,$N%G!<%?$KBP$7$F:F9=C[3X=,K!$rMQ$$$F:GE,2=$7$?!#3X=,$N<}B+$N$?$a$NogCM$O!"8m:9$N:GBgCM$,(B0.005$B$H$7$?!#(B
$BJPHyJ,78?t2r@O$O!"F~NO%Q%i%a!<%?$N46 $B#3G/4V$N(B51$B%G!<%?$rMQ$$$?JPHyJ,78?t$NJ?6QCM$r$=$l$>$l(BFigure 5$B$K<($7$?!#Hy78?t$NCM$O>.$5$/!"$3$l$i$NJQ?t$OC1FH$G$O$I$l$b$"$^$jBg$-$J1F6A$r>eN.!&CfN.!&2


Figure 5. Averaged differential coefficients (1997-1999)

$B$?$@-,COND, NH4-N$B$J$IHy78?t$,Bg$-$$$3$H$,H=$k!#$7$+$7$J$,$i$3$l$i$NJQ?t$OeN.!&CfN.$H2eN.$rJ,$1$kJQ?t$H$J$C$F$*$j!">eN.$rJ,N`$9$k%Q%i%a!<%?$O!"(BpH$B$H(BDO$B$G$"$k!#$3$N$h$&$KJPHyJ,78?t2r@O$OF~NO%Q%i%a!<%?$NJ,N`$KBP$9$k4sM?$r>\:Y$K$_$k$3$H$,$G$-$k!#(B
$B$5$i$K!"(BFigure 6$B$K3FG/EY$4$H$N%G!<%?$rMQ$$$?Hy78?t$NJ?6QCM$r<($7$?!#2=3XE*%Q%i%a!<%?$N>eN.!&CfN.!&2eN.$HCfN.$rJ,N`$9$k%Q%i%a!<%?$G$"$C$?$,!"(B1998$BG/$H(B1999$BG/$G$OCfN.$H2C$5$l$F$$$k798~$,8+$F


Figure 6. Averaged Differential Coefficients of 1997, 1998 and 1999

$B$^$?!"(BFigure 5$B$K<($9A4BN$N798~$H!"(BFigure 6$B$N(B1998$BG/$N798~$,$h$/;w$F$$$k$3$H$O!"(B1998$BG/$NCfN.0h$G$N(BNH4-N$B$KH?1G$9$k1x@w$,Bg$-$J$b$N$G$"$C$?$3$H$r<(:6$7$F$$$k!#(B

5 $B$^$H$a(B

$BB?K`@n$N(B17$BCOE@$K$*$1$k?eeN.!&CfN.!&2 $B3FCOE@$G$N%G!<%?$,$=$m$C$F$$$k(B12$BeN.!&CfN.!&2-$B$*$h$S(BCOND$B$,>eN.!&CfN.!&2 $B%K%e!<%i%k%M%C%H%o!<%/$rMQ$$$?JPHyJ,78?t2r@O$N7k2L$G$O!"(B12$B.$5$/!"$3$l$i$NJQ?t$OC1FH$G$O$I$l$b$"$^$jBg$-$J1F6A$r>eN.!&CfN.!&2-,COND, NH4-N$B$J$IHy78?t$,Bg$-$$$3$H$,H=$C$?!#$3$l$i$NJQ?t$OeN.!&CfN.$H2eN.$rJ,$1$kJQ?t$H$J$C$F$*$j!">eN.$rJ,N`$9$k%Q%i%a!<%?$O!"(BpH$B$H(BDO$B$G$"$k$3$H$,$o$+$C$?!#(B
$BB?K`@n$N?e/$5$;$k$3$H$,I,MW$G$"$k$3$H$,<(:6$5$l$?!#(B

$B$$$D$bM-1W$J8f5DO@$r$7$F$$$?$@$$$F$$$k!"$*Cc$N?e=w;RBg3X$N:YLp<#IW65>K\9bMxGn;N!"K-665;Bg$NA%DE8x?M=u65 $B;29MJ88%(B

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[11] $BJ!EDJ~;R(B,$BEDEg@!7C(B,$B:XF#5WEP(B,$BD9Eh1@J<(B,$B:YLp<#IW(B,$B@D;3CRIW(B, J. Chem. Software, 7, 115 (2001).


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